منابع مشابه
CNS Genes Implicated in Relapse
Drug abuse is a condition that impacts not only the individual drug user, but society as a whole. Although prevention of initial drug use is the most effective way to prevent addiction, avoiding relapse is a crucial component of drug addiction recovery. Recent studies suggest that there is a set of genes whose expression is robustly and stably altered following drug use and ensuing abstinence. ...
متن کاملCNS relapse in acute promyeloctyic leukemia.
A 42-year-old female was diagnosed with acute promyelocytic leukemia (APL) with a translocation of chromosomes 15 and 17 involving the PML and RARA genes. On presentation she met criteria for low-risk disease on the basis of platelet count (50 10/L) and WBC count (0.8 10/L). The patient achieved a complete molecular remission after induction chemotherapy with all-trans-retinoic acid (ATRA) and ...
متن کاملDoes Routine Imaging of Patients for Progression or Relapse Improve Survival in Rhabdomyosarcoma?
BACKGROUND Patients with rhabdomyosarcoma (RMS) who complete therapy typically undergo 4 years of surveillance imaging despite lack of evidence that this improves outcomes. We compared overall survival (OS) between patients in whom progression or relapse was detected by routine clinical evaluation or by imaging. PROCEDURE Children with progressive or relapsed RMS treated at Texas Children's H...
متن کاملHepatitis B vaccine and risk of relapse after a first childhood episode of CNS inflammatory demyelination.
Public concern about possible increases in the risk of multiple sclerosis associated with hepatitis B vaccination has led to low vaccination coverage. We investigated whether this vaccination after a first episode of acute CNS inflammatory demyelination in childhood increased the risk of conversion to multiple sclerosis. We studied the French Kid Sclérose en Plaques (KIDSEP) neuropaediatric coh...
متن کاملLow incidence of CNS relapse with cranial radiotherapy and intrathecal methotrexate in acute lymphoblastic leukemia.
OBJECTIVES To assess the incidence of isolated central nervous system (CNS) relapses in patients of acute lymphoblastic leukemia (ALL) treated with a protocol containing cranial irradiation and intrathecal methotrexate as CNS directed therapy. DESIGN Prospective non randomized study. SETTING Department of Medical Oncology, Tata Memorial Hospital. SUBJECTS 623 children of ALL on MCP 841. ...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2017
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2017.02.083